摘要
目的 运用数据挖掘方法分析总结王垂杰教授治疗慢性胃病的用药经验;
材料与方法 收集王垂杰导师2015年10月~2016年1月在辽宁中医药大学附属医院国医堂门诊诊治慢性胃病相关典型病例175例,通过Excel导出用药频数分析,运用SPSS19.0统计软件对筛选出的高频药物(频数大于20的35味药物)进行R型系统聚类分析,运用SPSSClementine12.0统计软件对高频药物(频数大于20的35味药物)进行关联规则分析。
结果 共录入病例175例,共分证型14种,应用中药113味,总用药频次2612次,频数大于等于20次的药物35味;聚类分析结果:从聚二类到聚六类中,聚四类的结果相对于其他分类较为合理;关联规则得出二元药物关联24对、三元药物关联26组、四元药物关联8组、五元药物关联1组;
结论 导师所治疗慢性胃病中以胃痛和胃痞病最多;证型以肝胃郁热、肝胃不和、脾胃湿热等实证为主;用药以理气药、补气药、清热药和化湿药四大类为主;得出治疗慢性胃病基础方3个;常用药对13对;得出导师治疗慢性胃病中肝胃不调证核心方药组合为:柴胡、栀子、黄连、陈皮、甘草;导师治疗慢性胃病的常用治法有疏肝和胃,清热化湿,健脾理气,行气止痛。
Study on the use of professor Wang Chuijie in the treatment of chronic stomach disease based on Data Mining
objective use data mining methods to analyze and summarize treatment of chronic gastropathy medication experience of Professor Wang ChuiJie; material and methods to collect Wang ChuiJie mentor October 2015 ~ 2016 years 1 month in 175 cases of Guo Yi Tang clinic in Affiliated Hospital of Liaoning University of traditional Chinese medicine diagnosis and treatment of chronic gastropathy related typical cases, through Excel export use frequency analysis, using SPSS statistical software to filter out high-frequency drugs (frequency is more than 20 35 drugs) of R type cluster analysis, using SPSSClementine12.0 statistical software of drugs with a higher frequency (frequency is more than 20 3 In depressed disease and 26 24 pairs with respect to the results of two 35 113 175 5 herbs) association rules analysis. Results a total of entry case, a total of card type 14, application of traditional Chinese medicine taste, medication frequency 2612 times, frequency is greater than or equal to 20 times the drug taste; cluster analysis results: from poly to poly six categories, poly four other classification is more reasonable; association rule that binary linked to the drug, three yuan linked to the drug group, four yuan linked to the drug group 8, 5 yuan of drug associated 1 group. Conclusion the tutor in the treatment of chronic gastropathy with gastralgia gastric ruffian; type of syndrome of liver and stomach heat, liver and stomach, spleen and stomach damp heat empirical; medication management Gas medicine, Qi tonic, antipyretic and dampness medicine mainly; draw the treatment chronic gastropathy base 3; commonly used drugs on 13 on; come to tutor treatment in chronic gastritis of liver and stomach does not adjust card core prescription combination, bupleurum root, gardenia, coptis root, dried tangerine peel, licorice; tutor treatment chronic gastropathy commonly used treatment of soothing the liver and regulating the stomach, clearing heat and removing dampness, invigorating spleen and regulating qi, Qi pain.