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NCCN临床实践指南:非小细胞肺癌(2024.V11)

指南制定者:美国国家综合癌症网络

出处:NCCN官网

发布时间:2024-10-15

1.指南来源(Guide Source):

NCCN临床实践指南:非小细胞肺癌 V11.2024.发布已获NCCN肿瘤学临床实践指南(NCCN指南®)许可。©2024美国国家综合癌症网络公司.保留所有权利。未经NCCN明确的书面许可,不得出于任何目的以任何形式复制NCCN指南®和文中的插图。要查看NCCN指南的最新完整版本,请访问NCCN.org。NCCN指南是一项持续进行的工作,可能会随着新的重要数据的出现而不断完善。 

2.免责声明(Disclaimers):

NCCN对其内容、使用或应用不做任何形式的担保,并否认以任何方式对其应用或使用承担任何责任。

在下载本篇指南前,请先您详细阅读并同意以下协议:

NCCN内容不得用于商业目的,以及NCCN作为NCCN内容的许可方,不作任何陈述或保证,并明确否认NCCN指南适用于任何特定患者的护理或治疗,任何医院、寻求使用《NCCN指南》治疗患者的临床医生或其他医疗服务提供者(“提供者”)应根据特定患者护理或治疗的具体临床情况做出独立的医疗判断,NCCN不建议、推荐或认可任何提供者(无论是否与被许可方相关)进行任何有偿或无偿的医疗治疗、咨询或服务,也不应因被许可方建议、推荐或认可任何此类提供者的作为或不作为而直接或间接承担责任。详见《NCCN最终用户许可协议》

3.专家名单(Staff):

David S. Ettinger, MD/Chair †The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

*Douglas E. Wood, MD/Vice Chair ¶Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance

Dara L. Aisner, MD, PhD ≠University of Colorado Cancer Center

Wallace Akerley, MD †Huntsman Cancer Institute at the University of Utah

Jessica R. Bauman, MD ‡ †Fox Chase Cancer Center

Ankit Bharat, MD ¶Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Debora S. Bruno, MD, MS †Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute

Joe Y. Chang, MD, PhD §The University of Texas MD Anderson Cancer Center

Lucian R. Chirieac, MD ≠Dana-Farber/Brigham and Women’s Cancer Center

Thomas A. D’Amico, MD ¶Duke Cancer Institute

Malcolm DeCamp, MD ¶University of Wisconsin Carbone Cancer Center

Thomas J. Dilling, MD, MS §Moffitt Cancer Center

Jonathan Dowell, MD †UT Southwestern Simmons Comprehensive Cancer Center

Scott Gettinger, MD † ÞYale Cancer Center/Smilow Cancer Hospital

Travis E. Grotz, MD ¶Mayo Clinic Cancer Center

Matthew A. Gubens, MD, MS †UCSF Helen Diller Family Comprehensive Cancer Center

Aparna Hegde, MD †O'Neal Comprehensive Cancer Center at UAB

Rudy P. Lackner, MD ¶Fred & Pamela Buffett Cancer Center

Michael Lanuti, MD ¶Massachusetts General Hospital Cancer Center

Jules Lin, MD ¶University of Michigan Rogel Cancer Center

Billy W. Loo, Jr., MD, PhD §Stanford Cancer Institute

Christine M. Lovly, MD, PhD †Vanderbilt-Ingram Cancer Center

Fabien Maldonado, MD £Vanderbilt-Ingram Cancer Center

Erminia Massarelli, MD, PhD, MS †City of Hope National Medical Center

Daniel Morgensztern, MD †Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

Thomas Ng, MD ¶The University of Tennessee Health Science Center

Gregory A. Otterson, MD †The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

Jose M. Pacheco, MD †University of Colorado Cancer Center

Sandip P. Patel, MD ‡ † ÞUC San Diego Moores Cancer Center

Gregory J. Riely, MD, PhD † Þ Memorial Sloan Kettering Cancer Center

Jonathan Riess, MD ‡UC Davis Comprehensive Cancer Center

Steven E. Schild, MD §Mayo Clinic Cancer Center

Theresa A. Shapiro, MD, PhD ¥ ÞThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Aditi P. Singh, MD †Abramson Cancer Center at the University of Pennsylvania

James Stevenson, MD †Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute

Alda Tam, MD фThe University of Texas MD Anderson Cancer Center

Tawee Tanvetyanon, MD, MPH †Moffitt Cancer Center

Jane Yanagawa, MD ¶UCLA Jonsson Comprehensive Cancer Center

Stephen C. Yang, MD ¶The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Edwin Yau, MD, PhD †Roswell Park Comprehensive Cancer Center

4.临床试验(Clinical Trials):

NCCN认为任何癌症患者都可以在临床试验中得到最佳治疗,因此特别鼓励患者参与临床试验。 寻找NCCN成员组:https://www.nccn.org/home/member-institutions

5.NCCN对证据和共识分类( NCCN Categories of Evidence and Consensus):

推荐均为2A类,除非另有说明,请参见下表:

  

NCCN 对证据和共识的分类 

1类 

基于高水平证据,NCCN一致认为此项治疗合理

2A类 

基于低水平证据,NCCN一致认为此项治疗合理

2B类 

基于低水平证据,NCCN基本认为此项治疗合理

3类 

基于任何水平证据,NCCN对此项治疗是否合理存在重大分歧 

6.NCCN首选分类( NCCN Categories of Preference):

所有建议均视为合理,请参见下表:

  

NCCN 优先使用分类 

首选干预方法 

若合适,可负担,则基于疗效、安全性和证据更优的干预方法

推荐的其他干预方法 

其他繁育方法可能疗效较低,毒性更多,或一句的数据不太成熟;或者具有相似疗效,但费用明显较高

某些情况下有用 

其他干预方法可能会用于选定的患者人群(根据推荐类型定义)